This finding suggested different OHC pattern of activity in ANSD patients.ĭistortion-product otoacoustic emissions (DPOAEs) are byproducts of the outer hair cells (OHCs) nonlinearity when two tones interact within the cochlea. Conclusionsĭespite normal DPOAEs recordings in ANSD patients, their amplitudes and DP I/O function are different from that of normal hearing subjects. The pattern of DPOAEs I/O function was different in ANSD and it was dependent on the frequency and intensity of the stimulus. ResultsĭPOAEs amplitudes were significantly higher in ANSD group when compared with control. All cases were subjected to basic audiological evaluation, DPOAEs I/O function recorded at four frequencies of 2f1-f2 and 5 intensity levels of L1 and L2. This work included 2 groups: control group (GI) composed of 20 normal hearing subjects and study group (GII) consisted of 20 patients with ANSD.
This study is designed to address whether the input/output function of distortion product OAEs (DPOAEs I/O) in ANSD patients is similar or different from normal hearing subjects. Auditory neuropathy spectrum disorder (ANSD) is characterized by normal OHCs function as shown by intact cochlear microphonics (CMs) and/or otoacoustic emissions (OAEs) absent or grossly abnormal auditory brainstem responses (ABRs) and absent middle ear muscle reflexes.
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